A few years ago I had an accident at work and ended up hurting my right wrist quite badly. A year later, I had surgery to repair the damage and was stuck in a massive splint (my third, actually, during the course of the injury) and couldn’t use my hand at all.
So I decided to get myself one of those Queensland Handwriting books and teach myself how to write left-handed. I can still do it a bit but the first time was definitely a hard adjustment. Turns out the word ‘crumb’ was my nemesis.